Quantitative susceptibility mapping of the midbrain in Parkinson's disease
نویسندگان
چکیده
منابع مشابه
Diagnosis of patients with Parkinson's disease using quantitative susceptibility mapping
Introduction: Parkinson'sdisease isassociated withirondeposition in the brain. The T2-weighted imaging, T2* mapping, R2 mapping and Quantitative Susceptibility Mapping (QSM) are three common methods to evaluating the iron deposition in brain. Among three methods the QSM is more sensitive than others. Few studies have been used QSM for evaluating the iron deposition in the basa...
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BACKGROUND Quantitative susceptibility mapping (QSM) and R2* relaxation rate mapping have demonstrated increased iron deposition in the substantia nigra of patients with idiopathic Parkinson's disease (PD). However, the findings in other subcortical deep gray matter nuclei are converse and the sensitivity of QSM and R2* for morphological changes and their relation to clinical measures of diseas...
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BACKGROUND This study explores the magnetostatic properties of the Alzheimer's disease brain using a recently proposed, magnetic resonance imaging, postprocessed contrast mechanism. Quantitative susceptibility mapping (QSM) has the potential to monitor in vivo iron levels by reconstructing magnetic susceptibility sources from field perturbations. However, with phase data acquired at a single he...
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.................................................................................................................................................... 2 Glossary of Terms ..................................................................................................................................... 3 Chapter 1: Introduction .......................................................................
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Introduction Huntington’s disease (HD) is a genetic disease that causes behavioral, cognitive, and motor dysfunction [1]. HD is caused by abnormal repetition (37 or more repeats) of a CAG sequence in the gene coding for the huntingtin protein. Excessive iron deposition in specific regions of the brain is associated with neurodegenerative disorders that include Huntington’s and Parkinson’s disea...
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ژورنال
عنوان ژورنال: Movement Disorders
سال: 2015
ISSN: 0885-3185
DOI: 10.1002/mds.26417